Semb B K, Hall K V, Nitter-Hauge S, Abdelnoor M
Thorac Cardiovasc Surg. 1983 May;31 Spec 2:61-5. doi: 10.1055/s-2007-1022031.
Throughout the period 1977 to 1982, 436 patients underwent aortic valve replacement (AVR), 106 underwent mitral valve replacement (MVR) and 56 patients underwent double valve replacement (DVR), with the Medtronic-Hall prosthetic valve (previous equivalent: Hall-Kaster valve). Early and late mortality were 4% and 9% for AVR, 8% and 11% for the MVR and 7% and 13% in the DVR, respectively. Actuarial survival after 5 years of follow-up was 80.9% for AVR, 75.4% for MVR and 81.0% for the DVR. Thromboembolic complications included 2 cases of valve thrombosis in the AVR, in one case secondary to valve endocarditis. Eleven further thromboembolic episodes occurred in 10 patients with AVR. In MVR an aspergillus thrombus was found on the valve at autopsy in a patient dying from multiple cerebral aspergillus abscesses. Five further thromboembolic episodes occurred in 4 patients with MVR. In the DVR group there was one valve thrombosis and one further patient with a thromboembolic episode. The actuarial probability of remaining free from thromboembolism at the end of the 5 years of follow-up was 92.5% for AVR and 83.7% for MVR.
在1977年至1982年期间，436例患者接受了主动脉瓣置换术（AVR），106例接受了二尖瓣置换术（MVR），56例患者接受了双瓣膜置换术（DVR），均使用美敦力-霍尔人工瓣膜（先前等效物：霍尔-卡斯特瓣膜）。AVR的早期和晚期死亡率分别为4%和9%，MVR为8%和11%，DVR为7%和13%。随访5年后的精算生存率，AVR为80.9%，MVR为75.4%，DVR为81.0%。血栓栓塞并发症包括AVR中有2例瓣膜血栓形成，其中1例继发于瓣膜心内膜炎。另外10例接受AVR的患者发生了11次血栓栓塞事件。在MVR中，1例死于多发性脑曲霉菌脓肿的患者尸检时发现瓣膜上有曲霉菌血栓。另外4例接受MVR的患者发生了5次血栓栓塞事件。在DVR组中，有1例瓣膜血栓形成，另有1例患者发生血栓栓塞事件。随访5年末无血栓栓塞的精算概率，AVR为92.5%，MVR为83.7%。
