混合性IgM-IgG冷球蛋白的细胞扩散沉淀分析。IgM成分一种不寻常的κ链决定簇。
Cell-diffusion precipitin analysis of mixed IgM-IgG cryoglobulins. An unusual kappa-chain determinant of the IgM component.
作者信息
Chernokhvostova E V, Batalova T N
出版信息
Immunol Lett. 1983 May;6(5):251-5. doi: 10.1016/0165-2478(83)90014-7.
PMID:6193059
Abstract
Antigenic features of monoclonal IgM kappa components of three mixed IgM-IgG cryoglobulins were studied by gel-diffusion precipitin analysis. An unusual kappa-chain determinant was revealed in the IgM components but not in other monoclonal immunoglobulins (IgM kappa, BJ kappa) or normal IgG. Antibodies to this determinant were found not only in anti-kappa, but also in anti-lambda sera, and in antisera to hidden determinants of L-chains.
摘要
通过凝胶扩散沉淀分析研究了三种混合IgM-IgG冷球蛋白的单克隆IgM κ成分的抗原特性。在IgM成分中发现了一种不寻常的κ链决定簇，但在其他单克隆免疫球蛋白（IgM κ、BJ κ）或正常IgG中未发现。不仅在抗κ血清中，而且在抗λ血清以及L链隐蔽决定簇的抗血清中都发现了针对该决定簇的抗体。
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