Protsenko O A, Anisimov P I, Mozharov O T, Konnov N P, Popov Iu A
Genetika. 1983 Jul;19(7):1081-90.
Plasmid DNA was isolated from Yersinia pestis strains containing pesticin I or fraction I antigen and "mouse" toxin determinants. Specificity of DNA preparations was studied by using them for transformation of plague agent strains carrying no plasmids. pPstI plasmid (molecular weight 7,0-7,8 MD) encoded pesticin I, fibrinolysin and plasmacoagulase synthesis. Fraction I antigen and "mouse" toxin production determinants were borne on pFraI/Tox plasmid (molecular weight about 50 MD). The observation that some Y. pestis cultures, having lost the ability to synthesize one of pFraI/Tox products, still retained this plasmid in their cells, is regarded as an evidence for a complicated regulation of pFraI/Tox function.
从含有鼠疫菌素I或I级分抗原以及“小鼠”毒素决定簇的鼠疫耶尔森氏菌菌株中分离出质粒DNA。通过将这些DNA制剂用于转化不携带质粒的鼠疫病原菌菌株来研究其特异性。pPstI质粒（分子量7.0 - 7.8 MD）编码鼠疫菌素I、纤维蛋白溶酶和血浆凝固酶的合成。I级分抗原和“小鼠”毒素产生决定簇位于pFraI/Tox质粒（分子量约50 MD）上。一些鼠疫耶尔森氏菌培养物失去了合成pFraI/Tox产物之一的能力，但细胞中仍保留该质粒，这一观察结果被视为pFraI/Tox功能存在复杂调控的证据。
