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结肠中蛋白酶激肽释放酶的免疫定位

Immunolocalization of the protease kallikrein in the colon.

作者信息

Schachter M, Peret M W, Billing A G, Wheeler G D

出版信息

J Histochem Cytochem. 1983 Nov;31(11):1255-60. doi: 10.1177/31.11.6194202.

DOI:10.1177/31.11.6194202
PMID:6194202
Abstract

Colon kallikrein was localized in the goblet cells of cat and man by a variety of immunocytochemical techniques. No evidence of this enzyme was found in other sites in this organ. The possible physiological significance of kallikrein in the gastrointestinal tract and of the many related serine proteases is discussed.

摘要

通过多种免疫细胞化学技术,发现结肠激肽释放酶定位于猫和人的杯状细胞中。在该器官的其他部位未发现这种酶的存在迹象。文中讨论了激肽释放酶在胃肠道中的可能生理意义以及众多相关丝氨酸蛋白酶的生理意义。

相似文献

1
Immunolocalization of the protease kallikrein in the colon.结肠中蛋白酶激肽释放酶的免疫定位
J Histochem Cytochem. 1983 Nov;31(11):1255-60. doi: 10.1177/31.11.6194202.
2
Immunocytochemical and enzyme histochemical localization of kallikrein-like enzymes in colon, intestine, and stomach of rat and cat.
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Localization of kallikrein in submandibular gland of cat, guinea pig, dog, and man by the immunoperoxidase method.用免疫过氧化物酶法对猫、豚鼠、狗和人的颌下腺中激肽释放酶进行定位。
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Enzyme- and immuno-histochemical localization of kallikrein. II. The human kidney.激肽释放酶的酶组织化学和免疫组织化学定位。II. 人肾。
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Localization of kallikrein in duct cells of submandibular gland in cat, dog, guinea-pig and man using immunocytochemical techniques [proceedings].利用免疫细胞化学技术对猫、狗、豚鼠和人类下颌下腺导管细胞中激肽释放酶的定位研究[会议论文集]
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The varied localization and functional significance of kallikrein-like enzymes in salivary glands, pancreas, colon, sex glands and spermatozoa, including evidence for the presence of nerve growth factor (NGF) in bull sperm acrosome.
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Ultrastructural immunolocalization of kallikrein in apical granules of striated duct cells of cat submandibular gland.猫下颌下腺纹状管细胞顶端颗粒中激肽释放酶的超微结构免疫定位
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引用本文的文献

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Bradykinin formation. Plasma and tissue pathways and cellular interactions.缓激肽的形成。血浆和组织途径以及细胞相互作用。
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Morphometric analysis of mucous granule depletion and replenishment in rat colon.大鼠结肠黏液颗粒消耗与补充的形态计量学分析
Dig Dis Sci. 1993 Dec;38(12):2299-304. doi: 10.1007/BF01299912.
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Molecular cloning, purification and in situ localization of human colon kallikrein.人结肠激肽释放酶的分子克隆、纯化及原位定位
Biochem J. 1995 Apr 15;307 ( Pt 2)(Pt 2):481-6. doi: 10.1042/bj3070481.
4
Immunolocalization of renal kallikrein-like substance in rat urinary bladder.大鼠膀胱中肾激肽释放酶样物质的免疫定位
Histochem J. 1993 Sep;25(9):664-9. doi: 10.1007/BF00157880.
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Pharmacological characterization of rabbit corpus cavernosum relaxation mediated by the tissue kallikrein-kinin system.组织激肽释放酶-激肽系统介导的兔海绵体舒张的药理学特征
Br J Pharmacol. 1994 Sep;113(1):81-6. doi: 10.1111/j.1476-5381.1994.tb16177.x.
6
Light microscopic immunocytochemical demonstration of peroxisomal enzymes in epon sections.环氧树脂切片中过氧化物酶体酶的光镜免疫细胞化学显示
Histochemistry. 1984;81(1):15-22. doi: 10.1007/BF00495395.
7
Kallikrein-gene expression in the rat gastrointestinal tract.大鼠胃肠道中激肽释放酶基因的表达。
Biochem J. 1989 Nov 15;264(1):133-6. doi: 10.1042/bj2640133.
8
Kinin effects on ion transport in monolayers of HCA-7 cells, a line from a human colonic adenocarcinoma.激肽对人结肠腺癌系HCA-7细胞单层中离子转运的影响。
Br J Pharmacol. 1985 Sep;86(1):3-5. doi: 10.1111/j.1476-5381.1985.tb09428.x.
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Secretory glycoconjugates of a mucin-synthesizing human colonic adenocarcinoma cell line. Analysis using double labeling with lectins.一种合成黏蛋白的人结肠腺癌细胞系的分泌性糖缀合物。使用凝集素双重标记进行分析。
Histochemistry. 1990;93(3):311-7. doi: 10.1007/BF00266394.
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Increased secretion of glandular-kallikrein in the bronchial washings induced by intravenous injection of leukotriene C4 in guinea-pigs.静脉注射白三烯C4诱导豚鼠支气管灌洗液中腺体激肽释放酶分泌增加。
Br J Pharmacol. 1992 Mar;105(3):632-8. doi: 10.1111/j.1476-5381.1992.tb09031.x.