Basle M F, Rebel A, Renier J C
Metab Bone Dis Relat Res. 1983;4(5):305-11. doi: 10.1016/s0221-8747(83)80004-6.
Light and electron microscopic examination of bone in reflex sympathetic dystrophy syndrome confirms that vascular disorders play an important role in the genesis of bone lesions. These vascular disorders lead to degeneration of osteocytes and demineralization of bone, with the disappearance of hydroxyapatite crystals. The neo-osteogenesis that follows resembles the different stages of fracture repair, with precocious elaboration of irregular, replacement woven bone, followed by osteoclastic resorption and the laying down of lamellar bone trabeculae. The bone lesions clearly appear to be a consequence of autonomic nervous system circulatory disorders.
反射性交感神经营养不良综合征中骨骼的光镜和电镜检查证实，血管紊乱在骨病变的发生中起重要作用。这些血管紊乱导致骨细胞退变和骨质脱矿，羟基磷灰石晶体消失。随后的新骨形成类似于骨折修复的不同阶段，先是早熟地形成不规则的替代编织骨，接着是破骨细胞吸收，然后是板层骨小梁的沉积。骨病变显然是自主神经系统循环紊乱的结果。
