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[以0.957 Gy/d的剂量率连续照射且总累积剂量为19.14 Gy后小鼠造血功能的恢复。I. 骨髓、脾脏和胸腺]

[Recovery of hematopoiesis in mice following a continuous irradiation with a dose rate of 0.957 Gy/d and a total accumulated dose of 19.14 Gy. I. Bone marrow, spleen and thymus gland].

作者信息

Macková N, Praslicka M

出版信息

Folia Haematol Int Mag Klin Morphol Blutforsch. 1983;110(4):564-71.

PMID:6196271
Abstract

This paper deals with the evaluation of histological changes in the bone marrow, spleen and thymus of mice after continuous irradiation with a dose rate of 0.957 Gy/day and a total accumulated dose of 19.14 Gy. Erythropoiesis in the spleen could be recovered quickly, significantly exceeding the spleen erythropoiesis of the controls on the seventh post-irradiation day. Myelopoiesis in the bone marrow could be recovered until the 21st day and erythropoiesis until the 28th day after the end of irradiation. Lymphopoiesis in the thymus could be recovered on the 28th day approximately and in the spleen roughly on the 60th day after the end of irradiation.

摘要

本文研究了以0.957 Gy/天的剂量率连续照射、总累积剂量达19.14 Gy后小鼠骨髓、脾脏和胸腺的组织学变化评估。脾脏中的红细胞生成可迅速恢复,在照射后第7天显著超过对照组的脾脏红细胞生成。骨髓中的髓细胞生成在照射结束后直到第21天可恢复,红细胞生成直到第28天可恢复。胸腺中的淋巴细胞生成在照射结束后大约第28天可恢复,脾脏中的淋巴细胞生成大致在第60天可恢复。

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