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Effect of minoxidil on cultured keratinocytes.

作者信息

Baden H P, Kubilus J

出版信息

J Invest Dermatol. 1983 Dec;81(6):558-60. doi: 10.1111/1523-1747.ep12523220.

DOI:10.1111/1523-1747.ep12523220
PMID:6196423
Abstract

Minoxidil has been shown to stimulate hair growth and these studies were undertaken to determine whether the drug had a direct effect on keratinocytes. Cultures of human epidermal cells were treated with minoxidil and it was found that they survived longer than control cultures. In addition, minoxidil prolonged the time that cells could be passed after reaching confluence. The results suggest that minoxidil slows the senescence of keratinocytes, which is similar to what has been found with epidermal growth factor.

摘要

相似文献

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Effect of minoxidil on cultured keratinocytes.
J Invest Dermatol. 1983 Dec;81(6):558-60. doi: 10.1111/1523-1747.ep12523220.
2
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Minoxidil: inhibition of proliferation of keratinocytes in vitro.米诺地尔:体外对角质形成细胞增殖的抑制作用。
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Effects of epidermal growth factor, fibroblast growth factor, minoxidil and hydrocortisone on growth kinetics in human hair bulb papilla cells and root sheath fibroblasts cultured in vitro.表皮生长因子、成纤维细胞生长因子、米诺地尔和氢化可的松对体外培养的人毛乳头细胞和根鞘成纤维细胞生长动力学的影响。
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Serial cultivation of normal human epidermal keratinocytes.正常人表皮角质形成细胞的连续培养。
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Effects of epidermal growth factor, fibroblast growth factor, minoxidil and hydrocortisone on growth kinetics in human hair bulb papilla cells and root sheath fibroblasts cultured in vitro.表皮生长因子、成纤维细胞生长因子、米诺地尔和氢化可的松对体外培养的人毛乳头细胞和根鞘成纤维细胞生长动力学的影响。
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