Gallo I, Frater R W
Thorac Cardiovasc Surg. 1983 Oct;31(5):288-90. doi: 10.1055/s-2007-1021998.
Animal testing has become mandatory for the development of new prosthetic heart valves. It is very expensive. Low mortality and morbidity are essential in controlling costs. A simple technique for atrioventricular valve replacement in dogs and sheep that includes normothermic cardiopulmonary bypass, the maintenance of a beating heart and the avoidance of excision of the natural valve is described. Results have been excellent.
对于新型人工心脏瓣膜的研发而言,动物实验已成为一项强制性要求。这一过程成本高昂。在控制成本方面,低死亡率和低发病率至关重要。本文描述了一种在犬类和绵羊身上进行房室瓣置换的简单技术,该技术包括常温体外循环、维持心脏跳动以及避免切除天然瓣膜。实验结果非常理想。