患有轻度神经发育障碍儿童的血清中放射受体可测定生长调节素水平。
Serum levels of radioreceptor-assayable somatomedins in children with minor neurodevelopmental disorders.
作者信息
Rasmussen F, Sara V R, Gustavson K H
出版信息
Ups J Med Sci. 1983;88(2):121-6. doi: 10.3109/03009738309178445.
PMID:6196894
Abstract
The somatomedins are a family of multitarget, growth-promoting hormones suggested to play a regulatory role in the central nervous system. Serum concentrations of somatomedins were determined by a radioreceptor assay in 26 patients (19 boys and 7 girls) with minor neurodevelopmental disorders. Five of these 26 patients showed high serum levels (greater than 2 S.D.) of somatomedins. It is concluded that patients with elevated concentrations of somatomedins might represent a pathogenetic subgroup.
摘要
生长调节素是一类多靶点、促进生长的激素，被认为在中枢神经系统中发挥调节作用。采用放射受体分析法测定了26例轻度神经发育障碍患者（19名男孩和7名女孩）的血清生长调节素浓度。这26例患者中有5例血清生长调节素水平较高（大于2个标准差）。得出的结论是，生长调节素浓度升高的患者可能代表一个致病亚组。
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