Volpi A, Piaserico P L
Minerva Med. 1983 Oct 13;74(39):2287-9.
The role of alfa2-macroglobulin in diabetic microangiopathy pathogenesis is described. A study of the behaviour of this protein in a group of diabetic patients with and without microangiopathy and in a control group of healthy patients has been carried out. It has been found that the protein greatly increases in diabetic patients with microangiopathy. On the basis of these results, it is suggested that dosage of alfa2-macroglobulin can be a possible test for evaluating microangiopathic complications in diabetes.
描述了α2-巨球蛋白在糖尿病微血管病变发病机制中的作用。对一组有和没有微血管病变的糖尿病患者以及健康对照患者群体中该蛋白的行为进行了研究。已发现,患有微血管病变的糖尿病患者体内该蛋白大幅增加。基于这些结果,有人提出,检测α2-巨球蛋白含量可能是评估糖尿病微血管并发症的一种可行检测方法。