Le Pendu J, Oriol R, Lambert F, Dalix A M, Lemieux R U
Vox Sang. 1983;45(6):421-5.
One B- and two A-specific radioimmunoassays detected A and B antigenic determinants in saliva of ABH nonsecretors. The A or B antigens found in saliva of nonsecretors had lower efficiency and higher heterogeneity, in the inhibition of the A or B assays, as compared to A or B antigens in saliva of ABH secretors. In the 3 assays, samples of nonsecretor Lewis positive donors (Lea) had less A or B antigens than samples of nonsecretor Lewis negative donors (Lec), suggesting that there is a competition between A or B and Le gene-specified products.
一种针对B抗原和两种针对A抗原的放射免疫测定法检测到ABH非分泌者唾液中的A和B抗原决定簇。与ABH分泌者唾液中的A或B抗原相比，非分泌者唾液中发现的A或B抗原在抑制A或B测定方面效率较低且异质性较高。在这三种测定法中，非分泌者Lewis阳性供体（Lea）的样本比非分泌者Lewis阴性供体（Lec）的样本含有更少的A或B抗原，这表明A或B与Le基因指定产物之间存在竞争。
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