长波紫外线辐射诱导色素沉着对晒伤的防护作用。

Sunburn protection by longwave ultraviolet radiation-induced pigmentation.

作者信息

Kaidbey K H, Kligman A M

出版信息

Arch Dermatol. 1978 Jan;114(1):46-8.

PMID:619782

Abstract

The role of melanin pigment in sunburn protection was investigated. Deep tans were induced over the backs of volunteers with repeated exposure to longwave ultraviolet radiation (UV-A). Melanogenesis was stimulated without an appreciable thickening of the stratum corneum. Two to three times the minimal erythema dose was required to produce redness in UV-A-tanned skin. Transmission studies through isolated corneum sheets revealed that specimens from tanned skin were about twice as efficient in filtering sunburn rays as stratum corneum from untanned skin. Tanning with UV-A does not provide a substantial resistance against sunburn.

摘要

对黑色素在晒伤防护中的作用进行了研究。通过让志愿者背部反复暴露于长波紫外线辐射（UV-A）来诱导深度晒黑。在角质层没有明显增厚的情况下刺激了黑色素生成。在UV-A晒黑的皮肤中产生发红需要两到三倍的最小红斑剂量。通过分离的角质层薄片进行的透射研究表明，来自晒黑皮肤的标本过滤晒伤射线的效率约为未晒黑皮肤角质层的两倍。用UV-A晒黑并不能提供对晒伤的实质性抵抗。