Jansén C T, Viander M
Acta Derm Venereol. 1983;63(5):384-7.
The natural killer (NK) cell activity of lymphocytes from 24 psoriatic patients was compared with that of 34 normal controls and 19 patients with non-psoriatic dermatoses. In the range of effector/target cell ratios used (6.25 to 100), the basal NK cell activity level was similar in the three groups. Moreover, both interferon alpha (IFN-alpha) and interferon gamma (IFN-gamma) augmented the NK cell activity to the same extent in psoriasis as in the two control groups. We conclude that this important natural cancer surveillance mechanism is functioning properly in psoriatic patients.
将24例银屑病患者淋巴细胞的自然杀伤（NK）细胞活性与34例正常对照者及19例非银屑病性皮肤病患者的进行比较。在所使用的效应细胞/靶细胞比例范围内（6.25至100），三组的基础NK细胞活性水平相似。此外，在银屑病患者中，α干扰素（IFN-α）和γ干扰素（IFN-γ）增强NK细胞活性的程度与两个对照组相同。我们得出结论，这种重要的天然癌症监测机制在银屑病患者中功能正常。
