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正常人和小脑疾病患者姿势摆动的量化分析。

Quantification of postural sway in normals and patients with cerebellar diseases.

作者信息

Diener H C, Dichgans J, Bacher M, Gompf B

出版信息

Electroencephalogr Clin Neurophysiol. 1984 Feb;57(2):134-42. doi: 10.1016/0013-4694(84)90172-x.

DOI:10.1016/0013-4694(84)90172-x
PMID:6198154
Abstract

Posturography was performed in 41 patients with cerebellar diseases by means of a force measuring platform using an on-line computer program which calculated sway path, sway area, antero-posterior and lateral sway components and the amount of visual stabilization. Postural ataxia was quantitatively studied in 8 patients with spinal ataxia (Friedreich's), 6 patients with vestibulocerebellar lesions, 11 patients with anterior lobe atrophy, 7 patients with hemispheral cerebellar lesions, and 9 patients with a disease affecting all parts of the cerebellum. Patients with lesions of the cerebellar hemispheres could not be separated from normals by means of posturography. Lesions of the spino-cerebellar afferents (Friedreich' ataxia) caused an omnidirectional low frequency sway with preserved visual stabilization. Patients with anterior lobe atrophy showed a predominant antero-posterior sway, often with a spontaneous high frequency body tremor around 3 Hz. Vestibulo-cerebellar lesions exhibited omnidirectional low frequency sway poorly stabilized by vision. Quantitative posturography helps to localize cerebellar lesions and allows for quantitative follow-up studies of cerebellar diseases.

摘要

通过测力平台并使用在线计算机程序对41例小脑疾病患者进行姿势描记,该程序可计算摆动路径、摆动面积、前后和侧向摆动分量以及视觉稳定量。对8例脊髓性共济失调(弗里德赖希共济失调)患者、6例前庭小脑病变患者、11例小脑前叶萎缩患者、7例小脑半球病变患者和9例累及小脑各部位疾病的患者进行了姿势性共济失调的定量研究。小脑半球病变患者无法通过姿势描记与正常人区分开来。脊髓小脑传入纤维病变(弗里德赖希共济失调)导致全向低频摆动,视觉稳定功能保留。小脑前叶萎缩患者表现为主要的前后摆动,常伴有约3Hz的自发性高频身体震颤。前庭小脑病变表现为全向低频摆动,视觉稳定功能较差。定量姿势描记有助于小脑病变的定位,并可对小脑疾病进行定量随访研究。

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