Andler W
Klin Padiatr. 1984 Jan-Feb;196(1):47-8. doi: 10.1055/s-2007-1025573.
Bleomycin is now firmly established in the treatment of germinative scrotal tumors. Because of its low bone-marrow toxicity it is used for a number of malignant diseases in combination with other cytostatic drugs. However, the pulmonary toxicity of Bleomycin therapy was pointed out at an early stage: it can lead to a fatal lung fibrosis (Blum et al. 1973). This paper considers the pulmonary side-effects on the basis of a case observed by the author.
博来霉素现已在生殖性阴囊肿瘤的治疗中得到广泛应用。由于其骨髓毒性较低，它常与其他细胞毒性药物联合用于多种恶性疾病的治疗。然而，博来霉素治疗的肺部毒性在早期就已被指出：它可导致致命的肺纤维化（布卢姆等人于1973年指出）。本文基于作者观察到的一个病例，探讨了其肺部副作用。
