迷走神经刺激对犬血清和胃窦黏膜中胃泌素浓度的影响。

Effect of vagal stimulation on the concentration of gastrin in serum and antral mucosa in dogs.

作者信息

Watayou T, Ramus N I, Thompson J C

出版信息

Arch Surg. 1978 Jan;113(1):87-9. doi: 10.1001/archsurg.1978.01370130089017.

DOI:10.1001/archsurg.1978.01370130089017

PMID:619864

Abstract

The concentration of gastrin in serum and antral mucosa was studied in anesthetized dogs after electrical stimulation of the antral branch vagus nerve. Vagal stimulation caused immediate and sustained release of gastrin into the circulation. After stimulation for one hour, the gastrin concentration of antral mucosa increased significantly. This suggests that vagal release of gastrin triggers its rapid synthesis.

摘要

在对麻醉犬的胃窦支迷走神经进行电刺激后，研究了血清和胃窦黏膜中胃泌素的浓度。迷走神经刺激导致胃泌素立即且持续释放到循环中。刺激一小时后，胃窦黏膜的胃泌素浓度显著增加。这表明迷走神经释放胃泌素触发了其快速合成。