Joles J A, Huisman G H, Camphuisen G, Charbon G A
Arch Int Physiol Biochim. 1983 Sep;91(3):223-31.
In splenectomized dogs swimming causes a stronger vasoconstriction in the kidney than treadmill running. Renal blood flow measured by electromagnetic flow probes decreased by 10% during treadmill running and by 37% during swimming. The renal perfusion remained low during 30 min after both running and swimming. Arterial pressure increased during running and during swimming. Phenoxybenzamine, an alpha-adrenergic blocking agent, practically abolished the changes in renal perfusion induced by exercise, but not those in arterial pressure. The changes in renal blood flow and arterial pressure were stronger than those found in a previous study in non-splenectomized dogs. We conclude that in splenectomized dogs sympathetic and adrenomedullary response during exercise is increased resulting in a stronger renal vasoconstriction and a more pronounced increase in arterial pressure, than in intact dogs.
在脾切除的狗中，游泳比跑步机跑步引起更强的肾血管收缩。用电磁血流探头测量的肾血流量在跑步机跑步时减少10%，在游泳时减少37%。跑步和游泳后30分钟内肾灌注仍保持较低水平。跑步和游泳时动脉压均升高。α-肾上腺素能阻滞剂酚苄明几乎消除了运动引起的肾灌注变化，但未消除动脉压变化。肾血流量和动脉压的变化比先前对未脾切除狗的研究中发现的变化更强。我们得出结论，与完整的狗相比，脾切除的狗在运动时交感神经和肾上腺髓质反应增强，导致更强的肾血管收缩和更明显的动脉压升高。
