Kapadia S E, de Lanerolle N C
Brain Res. 1984 Jan 30;292(1):33-9. doi: 10.1016/0006-8993(84)90887-4.
Ultrastructural morphological relationship between microvessels and neural elements containing serotonin-like immunoreactivity, substance P and methionine-enkephalin like immunoreactivity were studied in the monkey and cat brain. A close relationship between serotonin-like immunoreactive dendritic processes, enkephalin-like immunoreactive profiles and capillary basement membrane was observed; they were usually separated by a double layer of glial membrane. More importantly, serotonin and substance P-like immunoreactive dendritic profiles are reported in close approximation with capillary basement membrane with no glial limitans at the site of contact. These intimate morphological associations may be the basis for neural regulation of tonicity, permeability and chemosensor function in the brain microvasculature.
在猴和猫脑中研究了微血管与含有5-羟色胺样免疫反应性、P物质和甲硫氨酸脑啡肽样免疫反应性的神经成分之间的超微结构形态学关系。观察到5-羟色胺样免疫反应性树突状突起、脑啡肽样免疫反应性结构与毛细血管基底膜之间存在密切关系；它们通常被双层神经胶质膜分隔。更重要的是，据报道，5-羟色胺和P物质样免疫反应性树突状结构与毛细血管基底膜紧密相邻，接触部位没有神经胶质界膜。这些紧密的形态学联系可能是脑微血管张力、通透性和化学传感功能神经调节的基础。
