Jójárt I, Joó F, Siklós L, László F A
Neurosci Lett. 1984 Oct 12;51(2):259-64. doi: 10.1016/0304-3940(84)90561-5.
Peroxidase-antiperoxidase (PAP) immunocytochemistry at the electron microscopic level was used to describe the fine structural characteristics of vascular connections between vasopressin (VP)-immunoreactive neuronal elements and cerebral microvessels in the rat. In the majority of connections, somata or neural processes (mainly dendrites) showing VP-like immunoreactivity were separated from the vessel wall by thin glial processes. In addition, some VP-positive elements could establish direct contacts with the basal lamina of the endothelium or of a pericyte associated with the capillary bed. The findings provide immunocytochemical evidence that the vasopressinergic neuronal elements can directly innervate microvessels in the brain and thereby participate in regulating the local permeability of and the flow through the cerebral microvessels.
在电子显微镜水平上，采用过氧化物酶-抗过氧化物酶（PAP）免疫细胞化学方法来描述大鼠中加压素（VP）免疫反应性神经元元件与脑微血管之间血管连接的精细结构特征。在大多数连接中，显示VP样免疫反应性的胞体或神经突起（主要是树突）通过薄的神经胶质突起与血管壁分离。此外，一些VP阳性元件可与内皮或与毛细血管床相关的周细胞的基膜建立直接接触。这些发现提供了免疫细胞化学证据，表明加压素能神经元元件可直接支配脑内微血管，从而参与调节脑微血管的局部通透性和血流量。
