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糖尿病母亲患儿的临床病理研究。16例病例回顾

[Clinicopathologic study in children of a diabetic mother. Review of 16 cases].

作者信息

Carpio Utrilla O, Escobar Picasso E, Figueroa Tarango A

出版信息

Bol Med Hosp Infant Mex. 1978 Jan-Feb;35(1):109-14.

PMID:619922
Abstract

16 cases of infants of diabetic mothers were analyzed; 10 of them were live-born and died shortly afterwards; the other 6 were born dead. Among the live-born there was a high frequency of respiratory illnesses, neonatal jaundice and hemorrhagic tendency more often in lungs and C.N.S. At the necropsy, together with the findings atributtable to the mentioned illnesses there was also hyperplasia of the pancreatic islands in 100%, a high tendency to the visceral gigantism, specially in the liver, heart and lesser in the brain. And 20% had congenital malformations, chiefly in the C.N.S. genitourinary and lymphohematopoietic system. The descriptions are accompanied by a brief review of the literature.

摘要

对16例糖尿病母亲的婴儿进行了分析;其中10例活产,但随后不久死亡;另外6例出生时即为死胎。在活产儿中,呼吸系统疾病、新生儿黄疸以及肺部和中枢神经系统出血倾向的发生率较高。尸检时,除了上述疾病的表现外,100%的病例有胰岛增生,内脏巨大症倾向明显,尤其是肝脏和心脏,大脑较少见。20%的病例有先天性畸形,主要发生在中枢神经系统、泌尿生殖系统和淋巴造血系统。文中描述还伴有对相关文献的简要综述。

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