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干扰素成功治疗急性白血病患儿的水痘。

Successful treatment with interferon of chicken pox in children with acute leukemia.

作者信息

Kim B S

出版信息

Acta Med Okayama. 1984 Feb;38(1):71-8. doi: 10.18926/AMO/30370.

DOI:10.18926/AMO/30370
PMID:6199952
Abstract

Childhood leukemia, especially acute lymphocytic leukemia, can now be completely cured by a multimodality approach in one out of every two patients. Since prolonged maintenance therapy with anti-cancer agents for three years is required for complete cure, a significant problem during this course of treatment is death due to secondary infection. Those with childhood leukemia receiving anti-cancer chemotherapy who became secondarily injected with chicken pox can now be treated successfully with interferon in the four cases reported here. Chicken pox was cured even while one of them was in relapse. Therefore, it can be said that a bright prospect, namely interferon, is on the horizon in the treatment of secondary viral diseases associated with acute leukemia.

摘要

儿童白血病,尤其是急性淋巴细胞白血病,现在每两名患者中就有一人可通过多模式疗法完全治愈。由于完全治愈需要用抗癌药物进行为期三年的长期维持治疗,因此在这一治疗过程中的一个重大问题是继发感染导致的死亡。在此报告的4例接受抗癌化疗的儿童白血病患者继发水痘感染后,现在可用干扰素成功治疗。其中1例患者在复发时水痘也得以治愈。因此,可以说在治疗与急性白血病相关的继发性病毒疾病方面,干扰素展现出了光明的前景。

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