Garg S K, Abdurrahman M B, Momoh J T, Hargreaves H M, Narayana P, Lawrie J H
Ann Trop Paediatr. 1983 Dec;3(4):201-5. doi: 10.1080/02724936.1983.11748295.
There is scanty reference in the literature from the tropics, especially from Africa, to posterior urethral valves (PUV). The condition is not uncommon in Africans. Forty-five patients seen during a period of 10 years at the Ahmadu Bello University Hospital, Zaria, Nigeria have been analysed in order to discover any problems this abnormality may pose that are peculiar to the developing countries of the tropics. Two-thirds of the patients were under one year of age when first seen, one-third of them being under one month. About a quarter had no urological symptoms at presentation. Most of these were neonates and infants often critically ill due to sepsis and uraemia. These non-urological presentations caused delay in diagnosis and referral with detrimental effects on prognosis. However, the diagnosis could be made on clinical examination by demonstrating a palpable bladder and/or renal masses. Voiding cystourethrogram confirmed the diagnosis when carried out carefully, and required no specialized equipment. Most children were treated satisfactorily by perineal valve ablation, using simple inexpensive instruments. The death rate was high mainly due to delay in diagnosis and in starting appropriate treatment. It is suggested that amongst all who have care of children in the tropics, increased awareness of the varied clinical manifestations of PUV would improve prognosis.
热带地区,尤其是非洲地区的文献中很少提及后尿道瓣膜(PUV)。这种情况在非洲人中并不罕见。为了发现这种异常可能给热带发展中国家带来的任何特殊问题,对尼日利亚扎里亚阿哈马杜·贝洛大学医院在10年期间诊治的45例患者进行了分析。三分之二的患者初诊时年龄在1岁以下,其中三分之一在1个月以下。约四分之一的患者就诊时无泌尿系统症状。这些患者大多是新生儿和婴儿,常因败血症和尿毒症而病情危重。这些非泌尿系统表现导致诊断和转诊延迟,对预后产生不利影响。然而,通过触诊发现膀胱和/或肾脏肿块,可在临床检查时做出诊断。仔细进行排尿性膀胱尿道造影可确诊,且无需特殊设备。大多数儿童通过使用简单廉价的器械进行会阴瓣膜切除术得到了满意的治疗。死亡率高主要是由于诊断延迟和开始适当治疗延迟。建议在热带地区所有照顾儿童的人员中,提高对后尿道瓣膜多种临床表现的认识,这将改善预后。