Bar-Meir S, Halpern Z, Bardan E, Gilat T
Hepatology. 1984 Mar-Apr;4(2):328-30. doi: 10.1002/hep.1840040225.
Four hundred and fifty-four consecutive patients who had had their gallbladder removed were interviewed to determine the presence of upper abdominal pain, increased serum alkaline phosphatase and/or serum amylase activity. Patients with unexplained upper abdominal pain and/or enzyme abnormalities were offered endoscopic retrograde cholangiopancreatography (ERCP) and manometric evaluations. Dysfunction of the sphincter of Oddi diagnosed by ERCP manometry may account for the abdominal pain seen in 14% of the patients with postcholecystectomy syndrome. It may rarely be the cause of an elevated serum alkaline phosphatase and/or amylase when abdominal pain is not present. Papillary dysfunction is seen in less than 1% of the patients who have had their gallbladders removed. ERCP manometry is recommended in cholecystectomized patients with unexplained abdominal pain suggesting pancreaticobiliary origin.
对454例连续接受胆囊切除术的患者进行了访谈，以确定是否存在上腹部疼痛、血清碱性磷酸酶和/或血清淀粉酶活性升高。对有无法解释的上腹部疼痛和/或酶异常的患者进行了内镜逆行胰胆管造影（ERCP）和测压评估。通过ERCP测压诊断的Oddi括约肌功能障碍可能是14%的胆囊切除术后综合征患者出现腹痛的原因。当不存在腹痛时，它很少是血清碱性磷酸酶和/或淀粉酶升高的原因。在接受胆囊切除术的患者中，乳头功能障碍的发生率不到1%。对于有提示胰胆源性无法解释的腹痛的胆囊切除患者，建议进行ERCP测压。
