与所有杜克雷嗜血杆菌菌株发生反应的单克隆抗体。
Monoclonal antibodies reactive with all strains of Haemophilus ducreyi.
作者信息
Hansen E J, Loftus T A
出版信息
Infect Immun. 1984 Apr;44(1):196-8. doi: 10.1128/iai.44.1.196-198.1984.
Abstract
We have isolated plasma cell hybridomas which secrete monoclonal antibodies directed against Haemophilus ducreyi. Two of these monoclonal antibodies recognize all strains of H. ducreyi tested to date and are capable of detecting the presence of H. ducreyi in skin lesions produced by this pathogen in experimental animals. These monoclonal antibodies which react with apparently all strains of H. ducreyi have the potential to be developed into a rapid immunodiagnostic test for chancroid.
摘要
我们已经分离出了分泌针对杜克雷嗜血杆菌的单克隆抗体的浆细胞杂交瘤。其中两种单克隆抗体能识别迄今为止所检测的所有杜克雷嗜血杆菌菌株，并且能够检测出该病原体在实验动物皮肤损伤处产生的杜克雷嗜血杆菌。这些与显然所有杜克雷嗜血杆菌菌株都发生反应的单克隆抗体有潜力被开发成一种用于软下疳的快速免疫诊断测试。
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