Pritchett T R, Skinner D G
J Urol. 1984 May;131(5):970-1. doi: 10.1016/s0022-5347(17)50734-x.
An elevated serum alpha-fetoprotein is an important serum and cell marker in nonseminomatous testicular cancer. While the sensitivity of an elevated alpha-fetoprotein is 20 to 70 per cent, depending upon clinical stage subgrouping, the specificity is 100 per cent, since no falsely positive elevation of alpha-fetoprotein has been reported. We report a case of persistent falsely positive elevation of alpha-fetoprotein after curative therapy of embryonal carcinoma.
血清甲胎蛋白升高是非精原细胞瘤性睾丸癌的一项重要血清及细胞标志物。虽然血清甲胎蛋白升高的敏感性为20%至70%,具体取决于临床分期亚组,但特异性为100%,因为尚无甲胎蛋白假阳性升高的报道。我们报告1例胚胎癌根治性治疗后甲胎蛋白持续假阳性升高的病例。