Serum alpha-fetoprotein and human chorionic gonadotropin in the management of testicular tumors.

The new radioimmunoassays for AFP and beta-HCG are highly specific for nonseminomatous, germ-cell testicular tumor in genitourinary patients who do not have liver disease or other cancers. When used together, they are an accurate and sensitive indicator of metastases and are helpful in determining the effectiveness of therapy. However, they are not very useful in the differential diagnosis of scrotal masses.