乙醇对清醒犬脑血流量的影响。

The effects of ethanol on brain blood flow in awake dogs.

作者信息

Friedman H S, Lowery R, Archer M, Shaughnessy E, Scorza J

出版信息

J Cardiovasc Pharmacol. 1984 Mar-Apr;6(2):344-8. doi: 10.1097/00005344-198403000-00021.

DOI:10.1097/00005344-198403000-00021

PMID:6200726

Abstract

Ethanol produces a generalized decline in brain flow in awake dogs. The reduction in flow is most marked and persistent in the cerebellum. In the anesthetized animal with brain blood flow already depressed, this effect is obscured. The possible relationship of these findings to the acute and chronic effects of ethanol on the central nervous system in humans is discussed.

摘要

乙醇会使清醒犬的脑血流量普遍下降。血流量的减少在小脑最为显著且持续存在。在脑血流量已降低的麻醉动物中，这种效应会被掩盖。文中讨论了这些发现与乙醇对人类中枢神经系统的急性和慢性影响之间可能存在的关系。