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白化大鼠大脑皮层、纹状体和伏隔核中的神经化学不对称性。

Neurochemical asymmetries in the albino rat's cortex, striatum, and nucleus accumbens.

作者信息

Rosen G D, Finklestein S, Stoll A L, Yutzey D A, Denenberg V H

出版信息

Life Sci. 1984 Mar 19;34(12):1143-8. doi: 10.1016/0024-3205(84)90085-7.

DOI:10.1016/0024-3205(84)90085-7
PMID:6200745
Abstract

The concentrations of dopamine (DA), norepinephrine (NE), serotonin (5-HT), dihydroxyphenylacetic acid (DOPAC), and 5-hydroxyindoleacetic acid (5-HIAA) were measured in the right and left cortex, striatum, and nucleus accumbens of adult Purdue-Wistar rats. There was more DA in the right cortex and accumbens and a greater concentration of NE in the left striatum. There is more 5-HT in the left striatum and right accumbens, more 5-HIAA in the left cortex, as well as a greater 5-HT turnover in the left accumbens. These results are considered in the light of previous findings concerning the relationship of neurochemical asymmetries and behavioral lateralization.

摘要

在成年普渡-威斯塔大鼠的左右皮质、纹状体和伏隔核中测量了多巴胺(DA)、去甲肾上腺素(NE)、5-羟色胺(5-HT)、二羟基苯乙酸(DOPAC)和5-羟吲哚乙酸(5-HIAA)的浓度。右侧皮质和伏隔核中的多巴胺含量更多,左侧纹状体中的去甲肾上腺素浓度更高。左侧纹状体和右侧伏隔核中的5-羟色胺更多,左侧皮质中的5-羟吲哚乙酸更多,并且左侧伏隔核中的5-羟色胺周转率更高。根据先前关于神经化学不对称与行为偏侧化关系的研究结果对这些结果进行了考量。

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