Carlson J N, Glick S D
Department of Pharmacology and Toxicology, Albany Medical College, New York 12208.
Experientia. 1989 Sep 15;45(9):788-98. doi: 10.1007/BF01954054.
Cerebral laterality can no longer be considered an exclusively human trait, as over the last 15 years there has been an emergence of data to suggest that animal brains are also lateralized. Morphologic, chemical and behavioral indices of brain asymmetry in the rodent have been reported, and it is suggested that variations in the magnitude and direction of these indices are determined by a complex interaction of genetic, hormonal and experiential factors. Interindividual differences in cerebral laterality have been shown to covary with, or predict, individual differences in spatial behavior and stress reactivity, as well as susceptibility to stress pathology and drug sensitivity. Such findings suggest that it is possible to study individual differences in lateralized brain function through the use of animal models.
大脑偏侧性不再被认为是人类独有的特征，因为在过去15年里，有数据表明动物大脑也存在偏侧化。啮齿动物大脑不对称的形态学、化学和行为学指标已有报道，并且有人提出这些指标在大小和方向上的变化是由遗传、激素和经验因素的复杂相互作用决定的。大脑偏侧性的个体差异已被证明与空间行为和应激反应性的个体差异相关或可预测这些差异，以及对应激病理学的易感性和药物敏感性。这些发现表明，通过使用动物模型来研究大脑偏侧化功能的个体差异是可能的。
