L-色氨酸的降压作用并非由脑血清素介导。
Antihypertensive effects of L-tryptophan are not mediated by brain serotonin.
作者信息
Wolf W A, Kuhn D M
出版信息
Brain Res. 1984 Mar 19;295(2):356-9. doi: 10.1016/0006-8993(84)90985-5.
PMID:6201230
Abstract
L-Tryptophan produces a significant antihypertensive effect in spontaneously hypertensive rats while D-tryptophan does not change blood pressure. Both isomers of tryptophan significantly increase brain serotonin to the same extent at a time when the antihypertensive effect of L-tryptophan is maximal. Thus, the antihypertensive effects of L-tryptophan do not appear to be mediated by brain serotonin.
摘要
L-色氨酸对自发性高血压大鼠有显著的降压作用，而D-色氨酸不会改变血压。在L-色氨酸的降压作用达到最大时，色氨酸的两种异构体均能使脑内血清素显著增加至相同程度。因此，L-色氨酸的降压作用似乎不是由脑内血清素介导的。
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