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结肠直肠癌。284例治疗结果。

Carcinoma of the colon and rectum. Results of treatment in 284 cases.

作者信息

Nilsson E, Gregersen N P, Hartvig B, Sjödahl R

出版信息

Acta Chir Scand. 1984;150(2):177-82.

PMID:6202086
Abstract

Survival among 284 patients treated for colorectal cancer in the period 1971-1975 is reviewed. Surgery was performed in 93% of the total series, with curative intent in 55%. The crude and the corrected 5-year survival rates were 28 and 36% for all the patients and 51 and 64%, respectively, in the group with curative surgery. Dukes' classification (A, B, C) gave corrected 5-year survival rates of 92, 71 and 35%. No patient who underwent no or only palliative surgery, or whose tumour was non-classifiable according to Dukes, survived for five years. For patients admitted on emergency indications the crude 5-year survival was significantly lower than for those electively admitted (18 v. 33%). The recurrence rate among the patients treated with curative intent was 36% at the end of five years (24% in colonic and 49% in rectal cancer). The postoperative mortality (within 30 days of surgery) was 11% for all the patients and 6% in the curative surgery group.

摘要

对1971年至1975年期间接受治疗的284例结直肠癌患者的生存情况进行了回顾。在整个系列中,93%的患者接受了手术,其中55%的手术目的是治愈。所有患者的粗5年生存率和校正后5年生存率分别为28%和36%,而接受根治性手术的患者组分别为51%和64%。根据Dukes分期(A、B、C期),校正后5年生存率分别为92%、71%和35%。未接受手术或仅接受姑息性手术的患者,或肿瘤无法根据Dukes分期分类的患者,均无存活5年的情况。因急诊入院的患者,其粗5年生存率显著低于择期入院的患者(18%对33%)。接受根治性治疗的患者在5年末的复发率为36%(结肠癌为24%,直肠癌为49%)。所有患者的术后死亡率(术后30天内)为11%,根治性手术组为6%。

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