Pihl E, Hughes E S, McDermott F T, Price A B
Surg Gynecol Obstet. 1981 Oct;153(4):495-6.
A total of 1,315 patients were treated by potentially curative resection for a single primary malignant tumor of the large intestine. Thirty-five or 2.7 per cent of the patients subsequently presented with a recurrent tumor at the site of the anastomosis. Fourteen of these patients were treated by further operation with curative intention, resulting in a median cancer-specific survival time of 41 months. The prognosis after resection of a recurrence of the tumor at the suture line was significantly better, p=0.001, than for patients in whom no further resection or palliative operation only was performed. None of the latter has survived for more than 30 months after confirmation of the recurrence, with a median survival time of 8.5 months.
共有1315例患者因大肠单发原发性恶性肿瘤接受了潜在根治性切除术。其中35例(占2.7%)患者随后在吻合口部位出现复发性肿瘤。其中14例患者接受了旨在根治的进一步手术,中位癌症特异性生存时间为41个月。肿瘤在缝合线处复发后切除的预后明显更好(p = 0.001),优于未进行进一步切除或仅进行姑息性手术的患者。后者在复发确诊后无一人存活超过30个月,中位生存时间为8.5个月。