Kennedy T G
Aust J Biol Sci. 1983;36(5-6):531-43. doi: 10.1071/bi9830531.
The earliest sign of blastocyst implantation is an increase in endometrial vascular permeability which is localized in areas adjacent to blastocysts. The localized nature of this response suggests that it occurs in response to a signal from the blastocyst. It has been suggested that this signal may be physical in nature, or may be due to blastocyst-produced histamine, oestrogen or prostaglandins. The evidence for each of these is reviewed. At present, it is not possible to exclude any of these signals, which are not mutually exclusive, with certainty. The bulk of the evidence suggests that prostaglandins have an obligatory role in the initiation of implantation, but they may not be necessarily be of blastocyst origin.
囊胚着床的最早迹象是子宫内膜血管通透性增加，这种增加局限于囊胚相邻区域。这种反应的局部性质表明它是对囊胚发出的信号作出的反应。有人提出，这个信号可能是物理性质的，也可能是由于囊胚产生的组胺、雌激素或前列腺素。现将关于这些信号的证据进行综述。目前，无法确定排除这些并非相互排斥的信号中的任何一个。大量证据表明，前列腺素在着床起始过程中起必不可少的作用，但它们不一定来自囊胚。
