Jackwood D J, Saif Y M, Moorhead P D, Bishop G
Avian Dis. 1984 Jan-Mar;28(1):100-16.
The effect of serotype II infectious bursal disease virus (IBDV) isolates from turkeys on the homoral immune response of turkey poults was determined. Following exposure to the OH IBDV isolate, poults in two experiments were inoculated with sheep red blood cells, which is a T-dependent antigen, and poults in two other experiments were inoculated with Salmonella heidelberg O antigen, which is a T-independent antigen. Prior exposure to serotype II IBDV did not affect serum antibody titers to these antigens. IBDV infection also did not affect the concentrations of serum immunoglobulin M (IgM), IgG, or IgA in these poults. Bursa:body weight ratios of OH IBDV-infected poults were not significantly different from those of uninfected controls. In one experiment, the humoral immune response of poults to the LaSota Newcastle disease vaccine was not affected by infection with the MO IBDV isolate. Although no clinical infectious bursal disease was observed in any poult in these experiments, the serotype II IBDV isolates were infectious and transmissible in poults.
测定了来自火鸡的II型传染性法氏囊病病毒（IBDV）分离株对小火鸡体液免疫反应的影响。在两个实验中，接触OH IBDV分离株后的小火鸡接种了绵羊红细胞（一种T细胞依赖性抗原），在另外两个实验中，小火鸡接种了海德堡沙门氏菌O抗原（一种T细胞非依赖性抗原）。预先接触II型IBDV并不影响针对这些抗原的血清抗体滴度。IBDV感染也不影响这些小火鸡血清免疫球蛋白M（IgM）、IgG或IgA的浓度。感染OH IBDV的小火鸡的法氏囊与体重之比与未感染的对照组无显著差异。在一个实验中，小火鸡对LaSota新城疫疫苗的体液免疫反应不受MO IBDV分离株感染的影响。尽管在这些实验中的任何小火鸡身上均未观察到临床传染性法氏囊病，但II型IBDV分离株在小火鸡中具有传染性且可传播。
