Van Houtte P, MacLennan I, Poulter C, Rubin P
Cancer. 1984 Jul 15;54(2):223-7. doi: 10.1002/1097-0142(19840715)54:2<223::aid-cncr2820540208>3.0.co;2-1.
Thirty-one patients with superior sulcus tumor (Pancoast's syndrome) treated with radiation between 1967 and 1980 were reviewed. Doses ranged from 2000 to 7000 cGy delivered with a continuous schedule (23 patients) and a split course regimen (8 patients). The overall survival at 5 years was 18% (median, 17 months). Patients without bone erosion or scalene lymph node involvement (13 patients) had the best 5-year survival rate of 40%. Local control tended to correlate with the total dose and tumor extent; doses below 5000 cGy or bone invasion were associated with a higher rate of local failure. Primary external radiation is not only useful for palliation but can also cure some patients with superior sulcus tumor.
对1967年至1980年间接受放疗的31例肺上沟瘤（潘科斯特综合征）患者进行了回顾性研究。剂量范围为2000至7000 cGy，采用连续放疗方案（23例患者）和分段放疗方案（8例患者）。5年总生存率为18%（中位数为17个月）。无骨质侵蚀或斜角肌淋巴结受累的患者（13例）5年生存率最高，为40%。局部控制率往往与总剂量和肿瘤范围相关；剂量低于5000 cGy或有骨质侵犯的患者局部失败率较高。原发性外照射不仅对缓解症状有用，还能治愈一些肺上沟瘤患者。
