Flodgren P, Baldetorp L, Landberg T, Mercke C, Möller T, Svahn-Tapper G
Acta Radiol Oncol Radiat Phys Biol. 1978;17(6):463-74. doi: 10.3109/02841867809128177.
Patients with unresectable or inoperable bronchial carcinoma were treated with en-bloc irradiation of the tumour and the mediastinal lymph nodes to a total target absorbed dose of 40 Gy in 20 fractions. The first 52 patients were treated in one series and the last 45 patients in two series (split-course). Radiation adverse effects were only mild. The two regimens gave the same palliative results. The median survival was the same for the 2 groups (8 months). Most patients died in disseminated disease.
无法切除或不宜手术的支气管癌患者接受肿瘤及纵隔淋巴结整块照射,总靶区吸收剂量为40Gy,分20次照射。前52例患者作为一个疗程治疗,后45例患者分两个疗程(分割疗程)治疗。放疗不良反应仅为轻度。两种治疗方案的姑息治疗效果相同。两组患者的中位生存期相同(8个月)。大多数患者死于播散性疾病。