Hall N E, Wynder E L
Environ Res. 1984 Jun;34(1):77-86. doi: 10.1016/0013-9351(84)90077-x.
The presence of polyaromatic hydrocarbons in the particulate phase of diesel engine exhaust has raised questions concerning potential carcinogenicity of diesel exhaust exposure. A case-control study was conducted of 502 male lung cancer cases and 502 controls without tobacco-related diseases to investigate the association of occupational diesel exhaust exposure and lung cancer. Diesel exhaust exposure was appraised by job title. The results show no association between diesel exhaust exposure and risk of lung cancer. They do, however, show the strong association between smoking and lung cancer and as such highlight the importance of smoking information in studies of occupational effect on lung cancer risk.
柴油发动机尾气颗粒相中多环芳烃的存在引发了有关接触柴油尾气潜在致癌性的问题。对502例男性肺癌病例和502例无烟草相关疾病的对照者进行了一项病例对照研究，以调查职业性接触柴油尾气与肺癌之间的关联。通过工作职位评估柴油尾气接触情况。结果显示，柴油尾气接触与肺癌风险之间无关联。然而，结果确实显示出吸烟与肺癌之间存在强关联，因此突出了吸烟信息在职业因素对肺癌风险影响研究中的重要性。
