髓鞘相关糖蛋白（MAG）在视神经华勒氏变性中的作用

Myelin associated glycoprotein (MAG) in Wallerian degeneration of the optic nerve.

作者信息

Wender M, Wajgt A, Michałowska G, Tokarz E

出版信息

Exp Pathol. 1984;25(2):125-7. doi: 10.1016/s0232-1513(84)80019-5.

PMID:6202545

Abstract

The content of myelin associated glycoprotein (MAG) was studied in the rabbit optic nerves undergoing Wallerian degeneration after ophthalmectomy . MAG was estimated according to the method described by Matthieu and Quarles (1973). The results of the studies demonstrated only negligible changes in the content of MAG in the course of central Wallerian degeneration. These experiments do not support the assumption that the periaxionally localized MAG of the central myelin is as a rule seriously involved in subcellular mechanisms functioning in early stages of central demyelinating processes.

摘要

对眼球摘除术后发生沃勒变性的兔视神经中髓鞘相关糖蛋白（MAG）的含量进行了研究。MAG 是根据 Matthieu 和 Quarles（1973 年）描述的方法进行测定的。研究结果表明，在中枢性沃勒变性过程中，MAG 的含量仅发生了微不足道的变化。这些实验不支持这样一种假设，即中枢髓鞘中轴突周围定位的 MAG 通常会严重参与中枢脱髓鞘过程早期阶段的亚细胞机制运作。