Papanicolaou A C, Levin H S, Eisenberg H M
Neurosurgery. 1984 Apr;14(4):412-5. doi: 10.1227/00006123-198404000-00004.
An evoked potentials (EPs) paradigm that has been effective in demonstrating asymmetries in hemispheric activation during cognitive tasks was used to assess cerebral reorganization for language in recovered aphasics. Cortical click EPs were recorded bilaterally in normal volunteers, recovered aphasics who had sustained focal left hemisphere injury, and nonaphasic patients with diffuse injuries during a control condition of attending only to the click and during a verbal memory task. During that task, EP amplitude attenuation occurred in the left hemisphere for the normal subjects and the nonaphasic patients and in the right hemisphere for the recovered aphasics. These contrasting asymmetries in hemispheric activation suggest that a shift of hemispheric specialization for verbal processing contributes to the recovery of linguistic competence in adult aphasics.
一种在认知任务中有效证明半球激活不对称性的诱发电位（EP）范式被用于评估恢复性失语症患者语言功能的大脑重组情况。在仅关注点击声的对照条件下以及在言语记忆任务期间，对正常志愿者、曾遭受左侧半球局灶性损伤的恢复性失语症患者以及患有弥漫性损伤的非失语症患者双侧记录皮层点击诱发电位。在该任务期间，正常受试者和非失语症患者的左侧半球出现诱发电位幅度衰减，而恢复性失语症患者的右侧半球出现诱发电位幅度衰减。半球激活中这些相反的不对称性表明，言语加工的半球特化转移有助于成人失语症患者语言能力的恢复。
