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骨转移瘤的疼痛:放射治疗结果

Pain in osseous metastases: results of radiotherapy.

作者信息

Trodella Lucio, Ausili-Cefaro Giampiero, Turriziani Adriana, Marmiroli Luca, Cellini Numa, Nardone Luigia

机构信息

Istituto di Radiologia, Divisione di Radioterapia Oncologica, Policlinico 'A. Gemelli', Università Cattolica del Sacro Cuore, Largo A. Gemelli 8, 00168-RomeItaly.

出版信息

Pain. 1984 Apr;18(4):387-396. doi: 10.1016/0304-3959(84)90051-4.

Abstract

Seventy-nine patients with osseous metastases were prospectively evaluated bone pain. The evaluation of pain has been accomplished using the Keele Scale system. All cases have been treated with radiotherapy. The therapeutic response for analgesic effect has been evaluated in complete response (CR) when total disappearance of pain was present; in partial response (PR) with the reduction of at least 1 point on the Keele Scale: in non-responsive (NR) when patients showed worsening or no change in pain symptomatology during or following therapy. 51.8% have presented complete response, 36.8% partial response and 11.3% no response. The global response (CR + PR) has been 88.6%. This response was evaluated in relation to fractionating daily dose of radiotherapy and minimum dose necessary for analgesia.

摘要

对79例骨转移患者的骨痛进行了前瞻性评估。疼痛评估采用基尔量表系统完成。所有病例均接受了放射治疗。当疼痛完全消失时,镇痛效果的治疗反应评估为完全缓解(CR);基尔量表至少降低1分则为部分缓解(PR);若患者在治疗期间或治疗后疼痛症状恶化或无变化,则为无反应(NR)。51.8%的患者出现完全缓解,36.8%为部分缓解,11.3%无反应。总体缓解率(CR + PR)为88.6%。根据放射治疗的每日分次剂量和镇痛所需的最小剂量对该反应进行了评估。

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