Aafjes J H, van der Vijver J C, Schenck P E
Br Med J. 1978 Feb 4;1(6108):289-90. doi: 10.1136/bmj.1.6108.289.
Testicular biopsies of 142 oligozoospermic men were used to obtain a testicular biopsy score count. These scores were clearly related to the chance of fertility, in contra-distinction to data on hormone concentrations and from analysis of semen. In 36 patients with a score of 9-10 there were 15 pregnancies; in 59 patients with a score of 8-9, 12; and in 47 patients with scores below 8 there was only one successful pregnancy, though this last group also contained an additional three patients whose wives' pregnancies ended in miscarriages. Rating of testicular biopsies is more useful for proper evaluation of oligozoospermic patients than are data on hormone concentrations and from semen analysis. Proper evaluation of new treatments should be based on trials where experimental and control groups are matched on these ratings.
对142名少精子症男性进行睾丸活检以获得睾丸活检评分计数。这些评分与生育几率明显相关，这与激素浓度数据和精液分析结果形成对比。在36名评分为9 - 10分的患者中，有15例怀孕；在59名评分为8 - 9分的患者中，有12例怀孕；在47名评分低于8分的患者中，只有1例成功怀孕，不过最后一组中还有另外3名患者，其妻子怀孕后流产。与激素浓度数据和精液分析相比，睾丸活检评分对于准确评估少精子症患者更有用。对新治疗方法的正确评估应基于实验组和对照组在这些评分上相匹配的试验。
