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[无精子症和严重少精子症男性血清卵泡刺激素与睾丸活检组织学结果的相关性]

[Correlation between serum FSH and histological findings on testicular biopsy in men with azoospermia and severe oligozoospermia].

作者信息

Maier U, Spona J

出版信息

Wien Klin Wochenschr. 1982 Apr 30;94(9):242-4.

PMID:6812293
Abstract

In 51 infertile men with azoospermia or severe oligozoospermia the histological findings on testicular biopsy were compared with the preoperative serum FSH level. In cases of absence of spermatogenesis on testicular biopsy the FSH showed the expected highly significant "feed back" increase, whereas in cases of functioning, but highly pathological spermatogenesis the serum FSH level gave no indication of the type of dysspermatogenesis. Normal FSH levels were found in over 90% of men showing normal spermatogenesis with obstructive azoospermia. Hence, complete inspection of the testis, with attempted demonstration of spermatozoa in the epidydimis, is essential in these cases during testicular biopsy in order to avoid an unnecessary secondary operative refertilizing procedure (epidydimovasostomy) when the site of obstruction is the rete testis.

摘要

对51例无精子症或严重少精子症的不育男性,将睾丸活检的组织学结果与术前血清促卵泡激素(FSH)水平进行了比较。睾丸活检显示无精子发生的病例中,FSH呈现出预期的高度显著“反馈”性升高,而在精子发生功能存在但高度病理性的病例中,血清FSH水平并未提示精子发生障碍的类型。超过90%精子发生正常但患有梗阻性无精子症的男性FSH水平正常。因此,在这些病例进行睾丸活检时,对睾丸进行全面检查并尝试在附睾中发现精子至关重要,以便在梗阻部位为睾丸网时避免不必要的二次手术再生育程序(附睾输精管吻合术)。

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