Jost J O, Clemens M, Rühland D, Bünte H
Zentralbl Chir. 1984;109(8):527-31.
Infusing 6 mg of somatostatin continuously for 24 hours will lead to a reduction of pancreatic secretion and perfusion of the splanchnic area. Due to this mechanism, secretion is significantly reduced in case of pancreatic or small intestine fistulae. Somatostatin was applied continuously in 39 patients for a period of 7 days. This led to a healing of pancreatic fistulae in 85.7% and small intestine fistulae in 63.6% of cases.
连续24小时输注6毫克生长抑素会导致胰腺分泌减少以及内脏区域灌注减少。由于这一机制,在胰腺或小肠瘘的情况下,分泌会显著减少。对39例患者连续应用生长抑素7天。这使得85.7%的胰瘘和63.6%的小肠瘘得以愈合。