Kamiryo Y, Sakatoku J
Hinyokika Kiyo. 1983 Apr;29(4):401-10.
Recently, in many institutions, Serratia marcescens has been isolated more frequently. Therefore, we made a statistical analysis of S. marcescens infections. S. marcescens was isolated from the urine of 327 of the 1,773 patients admitted to our Department between 1975 and 1981. S. marcescens was the most frequently isolated organism in the urine of both inpatients and outpatients all of the 7 years. S. marcescens was often isolated in patients with some underlying disease, elderly patients or postoperative patients, in which case the individual defense mechanism protecting the patient from infections is often low. Because 276 of the patients who had S. marcescens infection had urethral indwelling catheters, S. marcescens infection may be nosocomial. The most effective antibiotic against S. marcescens was chloramphenicol followed by amikacin, sulfamethoxazole-trimethoprim, and fosfomycin. The effectiveness of gentamycin, dibekacin and kanamycin was not as high as expected.
最近，在许多医疗机构中，粘质沙雷氏菌的分离频率越来越高。因此，我们对粘质沙雷氏菌感染进行了统计分析。1975年至1981年间，在我们科室收治的1773例患者中，有327例患者的尿液中分离出了粘质沙雷氏菌。在这7年里，粘质沙雷氏菌是住院患者和门诊患者尿液中最常分离出的微生物。粘质沙雷氏菌常出现在患有某些基础疾病的患者、老年患者或术后患者中，在这种情况下，保护患者免受感染的个体防御机制往往较低。由于276例粘质沙雷氏菌感染患者留置了尿道导管，粘质沙雷氏菌感染可能是医院感染。对抗粘质沙雷氏菌最有效的抗生素是氯霉素，其次是阿米卡星、磺胺甲恶唑-甲氧苄啶和磷霉素。庆大霉素、地贝卡星和卡那霉素的有效性不如预期。
