MacArthur B S, Ackerman N B
Surg Gynecol Obstet. 1978 Jan;146(1):49-53.
The hospital records of 48 patients with infections due to Serratia marcescens were reviewed. Isolates from these patients had been cultured during the period from August 1973 through July 1975, at which time an increase in frequency of infections due to Serratia had been noted. Most of these patients were elderly males with chronic debilitating diseases. All patients had received antimicrobial therapy prior to the time Serratia was first isolated. The majority had had indwelling urinary catheters inserted during some period of their hospitalization. Isolates were obtained predominantly from the urinary tract. In six of the 11 patients who died, Serratia appeared to play a role in the outcome, and all three patients with Serratia septicemia died. Serratia marcescens can be a virulent pathogen with a high degree of resistance to antibacterial agents. Attention must be given to the use of a sterile technique for insertion of urinary catheters, frequent care and cleansing of the catheter-meatal junction and use of a closed drainage system.
回顾了48例粘质沙雷氏菌感染患者的医院记录。这些患者的分离株于1973年8月至1975年7月期间培养，当时已注意到粘质沙雷氏菌引起的感染频率有所增加。这些患者大多数是患有慢性衰弱性疾病的老年男性。所有患者在首次分离出粘质沙雷氏菌之前均接受过抗菌治疗。大多数患者在住院期间的某个时间段插入了留置导尿管。分离株主要从泌尿道获得。在11例死亡患者中的6例中，粘质沙雷氏菌似乎对结局有影响，并且所有3例粘质沙雷氏菌败血症患者均死亡。粘质沙雷氏菌可能是一种毒力较强且对抗菌剂具有高度抗性的病原体。必须注意在插入导尿管时使用无菌技术，对导管-尿道口连接处进行频繁护理和清洁，并使用封闭引流系统。
