Moffat K, Blumenkranz M S, Hernandez E
Can J Ophthalmol. 1984 Apr;19(3):130-3.
In 15 pigmented rabbits a pars plana lensectomy, vitrectomy and giant retinal tear with bullous retinal detachment were produced with maintenance of an intact anterior lens capsule. The incidence of subsequent rubeosis iridis, as detected angiographically, was compared with that in a control group of animals in whom the anterior lens capsule was not preserved but whose management was identical in all other respects. The rubeosis in the rabbits was angiographically identical to that seen in humans following vitrectomy, with immediate formation of a mossy hyperfluorescent surface membrane that leaked fluorescein extensively into the anterior chamber in the late phase of the angiography. It was possible to distinguish true neovascularization from breakdown of the blood-ocular barrier by the time and extent of the fluorescein leakage. Preservation of an intact anterior lens capsule reduced the incidence of unequivocal (florid) rubeosis from 73% to 33% (p less than 0.05).
在15只色素沉着的兔子身上进行了晶状体平坦部切除术、玻璃体切除术，并制造了巨大视网膜裂孔伴大泡性视网膜脱离，同时保持前囊膜完整。通过血管造影检测，将随后虹膜红变的发生率与另一组动物进行比较，该对照组动物未保留前囊膜，但在其他所有方面的处理相同。兔子的虹膜红变在血管造影上与人类玻璃体切除术后所见相同，在血管造影后期立即形成苔藓状高荧光表面膜，该膜大量渗漏荧光素进入前房。通过荧光素渗漏的时间和程度，可以区分真正的新生血管形成和血眼屏障的破坏。保留完整的前囊膜可使明确（明显）的虹膜红变发生率从73%降至33%（P<0.05）。
