人类肿瘤中的磷脂酶活性：通过细胞化学染色进行定位
Phospholipase activity in human tumors: localization by cytochemical staining.
作者信息
Fan D, Voelz H
出版信息
J Cancer Res Clin Oncol. 1984;107(3):242-4. doi: 10.1007/BF01032616.
Abstract
Phospholipase activity was localized for the first time by cytochemical staining at the plasma membrane of malignant cells in gastric adenocarcinomas by electron microscopy. This activity was not found in benign cells of the same tumor, e.g., in components of the connective tissue underlying the glandular epithelium, or in cells beyond the margin of the same tumor. Neither benign nor malignant cells of colorectal tumors, nor those in malignant melanoma, had any phospholipase activity that could be demonstrated by the method.
摘要
通过电子显微镜下的细胞化学染色，首次在胃腺癌恶性细胞的质膜上定位了磷脂酶活性。在同一肿瘤的良性细胞中未发现这种活性，例如在腺上皮下方的结缔组织成分中，或在同一肿瘤边缘以外的细胞中。结直肠肿瘤的良性和恶性细胞，以及恶性黑色素瘤中的细胞，均未显示出该方法可检测到的任何磷脂酶活性。
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