Ogloblina O G, Poliantseva L R, Paskhina T S
Vopr Med Khim. 1984 Mar-Apr;30(2):104-8.
Concentration of acid stable inhibitors (ASI)--metabolites of plasma inter-alpha-trypsin inhibitor--was measured in urine samples of healthy persons and of 6 patients with nephrotic syndrome by means of modified cross immunoelectrophoresis. There was obtained 2-25 mg of ASI (Mr 22,000 and 32,000) in diurnal urine samples of patients with nephrotic syndrome, which were 10-20 times higher as compared with these inhibitors level in the urine of healthy persons. The reverse correlation was established for the value of glomerular filtration and the lever of ASI (Mr 32,000) in the urine of patients with nephrotic syndrome.
采用改良交叉免疫电泳法，对健康人和6例肾病综合征患者的尿液样本中酸稳定抑制剂（ASI）——血浆α-胰蛋白酶抑制剂间代谢产物的浓度进行了测定。肾病综合征患者的日间尿液样本中获得了2-25毫克的ASI（分子量分别为22,000和32,000），与健康人尿液中这些抑制剂的水平相比，高出10-20倍。在肾病综合征患者的尿液中，肾小球滤过值与ASI（分子量32,000）水平呈负相关。
