Kawaguchi T, Tsuchida T, Matsushita H
Clin Chim Acta. 1978 Feb 1;83(1-2):7-12. doi: 10.1016/0009-8981(78)90200-0.
Human sera collected from normal subjects and diabetic patients were electrophoresed in an urea-containing gel. The albumin fraction separated into several bands. In normal fasting serum the fast-migrating Bands 1 and 2 were observed and the slower-migrating Bands 4 and 5 did not appear. After glucose administration Band 1 disappeared and Bands 4 and 5 appeared for the first time. In diabetic serum Bands 4 and 5 did not appear before or after glucose administration and this abnormality resembles the pattern in C57BL/KsJ-db/db mice but not C57BL/6J-ob/ob mice.
收集正常受试者和糖尿病患者的人血清，在含尿素的凝胶中进行电泳。白蛋白部分分离成几条带。在正常空腹血清中观察到快速迁移的带1和带2，较慢迁移的带4和带5未出现。给予葡萄糖后，带1消失，带4和带5首次出现。在糖尿病血清中，无论给予葡萄糖前后，带4和带5均未出现，这种异常类似于C57BL/KsJ-db/db小鼠的模式，但不同于C57BL/6J-ob/ob小鼠。
