有骨折和无骨折的绝经后女性血浆雄烯二酮、血浆雌酮以及雄烯二酮向雌酮转化率之间的关系。
The relation between plasma androstenedione, plasma oestrone and androstenedione to oestrone conversion rates in post-menopausal women with and without fractures.
作者信息
Pelc B, Marshall D H, Guha P, Khan M Y, Nordin B E
出版信息
Clin Sci Mol Med. 1978 Feb;54(2):125-31. doi: 10.1042/cs0540125.
PMID:620501
Abstract
- Plasma androstenedione, plasma oestrone and the conversion of plasma androstenedione into oestrone were measured in 19 post-menopausal women without fractures (six of them oophorectomized) and 18 with vertebral or femoral neck fractures (four of them oophorectomized). 2. In the series as a whole, the main determinant of the plasma oestrone level was the plasma androstenedione concentration. Only in the small oophorectomized group did the variation in conversion rate make a significant contribution to the variation in plasma oestrone. 3. The conversion rates were not different as between non-fracture and fracture cases but the mean plasma androstenedione and oestrone concentrations were lower (though not significantly) in the latter.
摘要
- 对19名无骨折的绝经后女性（其中6人已切除卵巢）和18名有椎体或股骨颈骨折的绝经后女性（其中4人已切除卵巢）进行了血浆雄烯二酮、血浆雌酮以及血浆雄烯二酮向雌酮转化的测定。2. 在整个系列中，血浆雌酮水平的主要决定因素是血浆雄烯二酮浓度。仅在小样本的卵巢切除组中，转化率的变化对血浆雌酮的变化有显著贡献。3. 非骨折病例和骨折病例之间的转化率没有差异，但后者的血浆雄烯二酮和雌酮平均浓度较低（尽管不显著）。
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